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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Cocaine
drug:
Mephedrone
Research Papers that Mention the Interaction
“Discussion and ConclusionsWithin the UK, diffusion of mephedrone may have been associated with an unprecedented combination of a particularly aggressive online marketing policy and a decreasing availability/purity of both ecstasy and cocaine.”
Mephedrone (4-methylmethcathinone; ‘meow meow’): chemical, pharmacological and clinical issues“The distribution of mephedrone in the body fluids and tissues of a subject found dead after the concomitant intake of cocaine and mephedrone is reported.”
“In conclusion, cocaine and mephedrone may have additive locomotor stimulant effects, although further assessment with a wider range of dose combinations must be evaluated.”
“In combination with mephedrone, cocaine shifted the mephedrone dose-effect curve upwards in an infra-additive manner.”
“The self-administration data suggest that mephedrone is less reinforcing than cocaine, but that a history of responding for cocaine can increase the reinforcing effects of mephedrone.”
Effects of cocaine on the discriminative stimulus and reinforcing effects of mephedrone in male rats
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