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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Cocaine and Lobeline



Research Papers that Mention the Interaction

However, 1.0 mg/kg lobeline attenuated cocaine (10 and 20 mg/kg)-induced hyperactivity after repeated administration and prevented the development of sensitization to these cocaine doses.
The present results indicate a complex interaction of lobeline with cocaine and support other research indicating a role for nicotinic receptors in the development of sensitization to psychostimulants.
This study determined if lobeline alters cocaine-induced hyperactivity and if lobeline alters the induction and/or expression of sensitization to cocaine.
Life sciences  •  2006  |  View Paper