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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cocaine
drug:
Levorphanol
Research Papers that Mention the Interaction
“The high-efficacy mu opioid levorphanol , and the low-efficacy opioids buprenorphine, butorphanol, nalbuphine and (−)-pentazocine, dose-dependently enhanced the effects of cocaine at doses that did not alter locomotor activity when administered alone.”
Interactions between opioids and cocaine on locomotor activity in rats: influence of an opioid's relative efficacy at the mu receptor“Pretreatment with …/kg), levorphanol (0.03 and 0.1 mg/kg) and methadone (0.1 and 0.3 … (3.0 and 5.6 micrograms/kg), potentiated the discriminative stimulus effects of cocaine such that the cocaine dose-effect functions were shifted … reduced maximally by about one order of magnitude.”
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