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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Altogether, these findings demonstrate that L‐DOPA efficaciously reduces the reinforcing and motivational effects of cocaine likely potentiating dopamine transmission in the mPFC.”
“We found that L‐DOPA reduced cocaine self‐administration under FR‐1 schedule of reinforcement and decreased the breaking points and the amount of cocaine self‐administered under the progressive ratio schedule of reinforcement.”
Levodopa prevents the reinstatement of cocaine self‐administration in rats via potentiation of dopamine release in the medial prefrontal cortex“However, methamphetamine increases, but cocaine decreases the extracellular levels of DOPA.”
“These newly discovered “enterochromaffin-like” cells, which normally store neither catecholamines nor 5-hydroxytryptamine, can take up L-DOPA (or 5-hydroxytruptophan) by an active mechanism that can be blocked with cocaine.”
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