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“ Labetalol represents an effective first-line treatment, which, unlike benzodiazepines, directly counters the pharmacologic effects of cocaine and has no respiratory or sedative side effects.”
The Journal of emergency medicine • 2017 | View Paper
“Yet another distinctive aspect of this case is the use of labetalol for rapid resolution of hypertension, tachycardia, anxiety, and chest pain induced by cocaine and methamphetamine.”
The American journal of emergency medicine • 2017 | View Paper
“Propranolol, atenolol, and labetalol all antagonized the tachycardiac effect of cocaine in a dose-dependent manner, while the beta-2 antagonist ICI 118,551 did not.”