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Last Updated: 2 years ago

Possible Interaction: Cocaine and Ginseng

supplement:

Cocaine

supplement:

Ginseng

Research Papers that Mention the Interaction

Interestingly, ginseng also inhibited the appearance of the recurrent phenomenon (reappearance of the sensitized state was observed at the time of readministration of MAP and cocaine even after a 30-day discontinuation of drug administration) of the effect of MAP and cocaine.
On the other hand, behavioral sensitization (reverse tolerance to ambulation-accelerating effect) to morphine, methamphetamine (MAP) and cocaine was also inhibited by ginseng.
The conditioned place preference of MAP and cocaine was completely blocked by ginseng.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica  •  2001  |  View Paper
Interestingly, ginseng also inhibited the appearance of the recurrent phenomenon (reappearance of the sensitized state was observed at the time of readministration of methamphetamine and cocaine even after a 30-day discontinuation of drug administration) of the effect of methamphetamine and cocaine.
On the other hand, behavior sensitization (reverse tolerance to their ambulation-accelerating effect) to morphine, methamphetamine and cocaine was also inhibited by ginseng.
Methods and findings in experimental and clinical pharmacology  •  1998  |  View Paper
These results provide evidence that GE may be useful clinically for the prevention of adverse actions of MA and cocaine.
Pharmacology Biochemistry and Behavior  •  1996  |  View Paper
Intraperitoneal administration of ginseng total saponin (GTS, 100 and 200 mg/kg of body weight) prior to and during chronic administration of cocaine inhibited the development of reverse tolerance.
Pharmacology Biochemistry and Behavior  •  1995  |  View Paper