“In order to further investigate ghrelin’s role in dopamine-mediated reward, the present report examined whether pretreament with ghrelin , administered directly into the ventral tegmental area (VTA) of the midbrain, would potentiate the rewarding properties of cocaine as measured by CPP.”
“Our results indicated that both cocaine and ghrelin elicited CPP and that ghrelin pre-treatment potentiated the effect of cocaine on place preference.”