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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Cocaine and Gaba Agonists

supplement:

Cocaine

Research Papers that Mention the Interaction

RATIONALE There is evidence that prefrontal lobe GABA levels are low in cocaine-dependent (CD) individuals, and treatment with GABA agonists decreases cocaine self-administration.
Psychopharmacology  •  2005  |  View Paper
An intra-ventral tegmental area (VTA) injection of a cocktail of γ-aminobutyric acid (GABA)B and GABAA receptor agonists (baclofen and muscimol, respectively) immediately before the posttest inhibited the expression of cocaine CPP.
Biological & pharmaceutical bulletin  •  2017  |  View Paper