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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Cocaine and Flupirtine

supplement:

Cocaine

Research Papers that Mention the Interaction

FLU (20 mg/kg), injected concurrently with cocaine during conditioning, reduced the development of cocaine conditioned place preference.
The disruption of cocaine place preference by FLU suggests that KCNQ2/3 channels influence cocaine’s rewarding effects.
We tested the hypothesis that flupirtine (FLU) (2.5, 10, 20 mg/kg), a KCNQ2/3 agonist, reduces cocaine (15 mg/kg) conditioned place preference.
Behavioural pharmacology  •  2017  |  View Paper