“ FLU (20 mg/kg), injected concurrently with cocaine during conditioning, reduced the development of cocaine conditioned place preference.”
“The disruption of cocaine place preference by FLU suggests that KCNQ2/3 channels influence cocaine’s rewarding effects.”
“We tested the hypothesis that flupirtine (FLU) (2.5, 10, 20 mg/kg), a KCNQ2/3 agonist, reduces cocaine (15 mg/kg) conditioned place preference.”