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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Estradiol modulates the rewarding and reinforcing properties of cocaine in females, including an increase in selection of cocaine over alternative reinforcers.”
Estradiol increases choice of cocaine over food in male rats“ Abstract Estradiol potentiates behavioral sensitization to cocaine as well as self-administration of cocaine and other drugs of abuse in female rodents.”
“Animal studies have demonstrated that estrogen 17β-estradiol or E2) enhances the rewarding properties of cocaine.”
“However, whether estradiol enhances the neurochemical response to cocaine by acting in the mPOA is still unclear.”
“Furthermore, the current findings suggest that estradiol may enhance the rewarding properties of cocaine in female quail. (”
“Preclinical studies show that estradiol enhances sensitization to cocaine in females by mechanisms not fully understood.”
“CONCLUSIONS With these experiments, we show that there are sex differences in the effects of es radiol to preferentially enhance the response to coc aine in the DLS over the NAc in females, which may contribute to the preferential sensitization of stereotypy in females.”
“In females, estradiol enhances the behavioral response to cocaine.”
“Our laboratory has focused on the role of estradiol in modulating the response to cocaine.”
“These data hint that in females, estradiol modulates the behavioral effects of cocaine by regulating mu and kappa opioid signaling in mesocorticolimbic brain structures.”
“Up-regulation of cocaine- and amphetamine-regulated transcript contributes to the neuroprotective effects of estradiol.”
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