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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Cocaine and Escitalopram

supplement:

Cocaine

Research Papers that Mention the Interaction

Consistent with preclinical data, serotonin-modulating drugs like escitalopram may have acute effects on cocaine cue reactivity in human cocaine users.
On day 1 (acute phase), escitalopram produced a significantly greater decrease from baseline than placebo in attentional bias measured by cocaine Stroop task 5 hours post-dose.
Journal of psychopharmacology  •  2013  |  View Paper
However, acute treatment with ESC dose-dependently decreased the cocaine-seeking behavior and relapse triggered by cocaine priming or drug-associated conditioned cues in both OBX and SHAM rats.
Brain Research  •  2017  |  View Paper