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“The temporal concordance between cocaine-induced stimulation of ACTH, epinephrine and subjective euphoria suggests that these hormonal changes are significant concomitants of the abuse-related effects of cocaine.”
Pharmacology Biochemistry and Behavior • 2001 | View Paper
“Results showed that the addition of adrenaline significantly reduced the systemic absorption of cocaine during surgery but caused no significant increase in toxic cardiovascular effects compared with the use of cocaine alone.”
Clinical otolaryngology and allied sciences • 1988 | View Paper
“In addition, recent use of cocaine increases the risk of a medical emergency during dental treatment, especially when epinephrine-containing local anaesthetics or retraction cords are used.”
Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru • 2015 | View Paper
“Patients at higher risk for serious adverse effects from epinephrine are those with comorbidities such as underlying heart disease and those taking monoamine oxidase inhibitors, tricyclic antidepressants, antiarrhythmics, and cocaine [8].”
The American journal of emergency medicine • 2013 | View Paper
“ Cocaine is an indirect sympathomimetic agent that acts in the nervous system to block the presynaptic reuptake of serotonin and catecholamines (dopamine, norepinephrine and epinephrine ) and to increase their bioavailability at the post-synaptic receptors.”