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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cocaine
Research Papers that Mention the Interaction
“ Cocaine produced a slight (P = 0.08) decrease (22% reduction at 50 μm) in the tubular uptake of L‐DOPA.”
Studies on the pharmacology of the inward transport of L‐DOPA in rat renal tubules“Reduced steady state formation of dihydroxyphenylalanine (DOPA) (47%) was found in the nucleus accumbens (N. ACC) of rats treated with ten days of repeated cocaine (10 mg/kg, i.p.)”
“Chronic … of cocaine HCl (10 mg/kg, IP, every 12 hours for 10 … days) resulted in a significantly decreased rate of accumulation of 3,4-dihydroxyphenylalanine following decarboxylase inhibition (-27 to -33%) and of homovanillic acid following probenecid treatment (-25 to -34%) in rat striatum, limbic forebrain and midbrain.”
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