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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Cocaine
drug:
Bifeprunox
Research Papers that Mention the Interaction
“ResultsCariprazine, as … aripiprazole and bifeprunox , were able to reduce … rewarding effect of cocaine (minimum effective doses were 0.17, 1, and 0.1 mg/kg, respectively) and attenuated relapse to cocaine … with half maximal effective dose [ED50] values of 0.2, 4.2, and 0.17 mg/kg, respectively.”
Cariprazine (RGH-188), a D3-preferring dopamine D3/D2 receptor partial agonist antipsychotic candidate demonstrates anti-abuse potential in rats“Specifically, cariprazine, as well as aripiprazole and bifeprunox , was able to reduce the rewarding effect of cocaine and attenuated relapse to cocaine seeking in rats.”
Dopamine D3 partial agonists in the treatment of psychosis and substance use disorder comorbidity: a pharmacological alternative to consider?
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