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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Cobaltous Cation
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ Ca2+ (10 mM) and Co2+ (10 mM) activated the velocity of Asp1 liberation from A-II to 140% and 120%, respectively at 22 degrees C. Ca2+ (10(-1) M) and Co2+ (10 mM) also enhanced 125I A-II binding about 130%.”
Effects of low molecular weight peptides and divalent cations on degradation and binding of angiotensin II.“The cells were perfused with low-Na+ (60 mM) Tyrode's solution, and Ca2+ and K+ currents were blocked by external Co2+ (3 mM) and internal Cs+ (140 mM), respectively.”
Inhibitory effects of palmitoylcarnitine and lysophosphatidylcholine on the sodium current of cardiac ventricular cells“Cd2+, Ni2+, Co2+ , Mn2+, Mg2+ all block Ca currents, as do barbiturates, D-600 and nifedipine.”
“Furthermore, the addition of Co2+ , a nonspecific Ca2+ channel blocker, delayed the increase of Ca2+i and subsequent cell death.”
“Removal of extracellular calcium and addition of calcium channel blockers Co2+ ) greatly attenuated the increase in Ca2+i in response to anoxia but did not prevent cell swelling and injury.”
“Glutamate‐stimulated [3H]‐dopamine release was well maintained (60‐82% of control) in the presence of Co2+ , which blocks Ca2+ action potentials, and was unaffected by the local anesthetic, lidocaine.”
“ Co2+ , Ni2+ and Mn2+ had no activating effects on the activity in the absence of Ca2+, but was slightly reduced in the presence of Ca2+ (0.5 mM).”
“This effect is dependent on extracellular Ca2+ and is reduced by Ca2+ channel blockers such as Co2+ , D 600, and nifedipine.”
“Moreover, the addition of calcium antagonists such as Ni2+ and Co2+ (5 mM) to an incubation mixture containing Ca2+ (1 mM) resulted in the complete inhibition of coendocytosis without affecting endocytosis.”
“Moreover, the response occurring at suboptimal concentration of Ca2+ (0.4 mM) was potentiated by the concomitant addition of either Mg2+, Mn2+ or Co2+.”
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