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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cobalt
drug:
Penicillins
Research Papers that Mention the Interaction
“It has been shown … the antibacterial action of penicillin in vitro and in vivo may be markedly … by the presence of appropriately low concentrations of cobalt that do not themselves inhibit proliferation of the test organisms (Pratt and …, 1947b; Pratt, Dufrenoy, and Strait, 1948; Strait, Dufrenoy, and Pratt, 1948).”
Cytochemical Mechanisms of Penicillin Action“… cobalt to the nutrient agar in … the effectiveness of relatively dilute penicillin solutions in producing inhibition zones on plates seeded with Staphylococcus aureus and decreases to approximately one-third or less, … is used, the minimum or threshold concentration of penicillin that can be detected by the cylinder-plate technic.”
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