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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cobalt
drug:
Nitric Oxide
Research Papers that Mention the Interaction
“ Cobalt caused rise of PE-induced contractions as a result of the endothelial generation of ROS, by decreasing bioavailability of NO.”
Cobalt-Induced Hypercontraction is Mediated by Generationof Reactive Oxygen Species and Influx of Calcium in Isolated RatAorta“High levels of cobalt significantly up-regulated iNOS mRNA and protein expression, which resulted in the release of NO.”
“ NO donors reduced a cobalt insensitive background outward current between -70 and -30 mV. This response was mimicked by 8-Br-cGMP.”
“This illustrates how the cobalt center may serve to fine-tune the electronic communication between the NO ligand and its binding site.”
Ammonia-modified Co(II) sites in zeolites: spin and electron density redistribution through the Co(II)-NO bond.“A sensor for nitric oxide is reported that uses a novel redox matching mechanism to induce a resistance change upon binding this important ligand to cobalt.”
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