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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Cobalt
supplement:
Methionine
Research Papers that Mention the Interaction
“2 Amlodipine (0.5–2 × 10−4 M), verapamil (… × 10−4 M), lignocaine (0.1–2 × 10−3 M) … cobalt (2–6 × 10−2 M) in descending order of potency, but not nifedipine (1–5 × …, then abolished, the amplitude and number of action potentials in a concentration‐dependent manner.”
“ Cobalt (2 × 10−3 M ) inhibited, significantly, the stimulation‐evoked overflow of 3H.”
Effects of calcium channel antagonists on action potential conduction and transmitter release in the guinea‐pig vas deferens“Although L-methionine cannot be considered an effective antidote, it is likely to reduce partially the toxic effects of cobalt.”
“Both methionine and cysteine reduced cobalt accumulation in the liver and kidney, but the liver was affected to a greater extent than the kidney.”
“It was supposed that cobalt stimulated the B12-dependent synthesis of methionine , being the source of the methyl groups for biosynthesis of the methylated components of gentamicin complex.”
[Role of cobalt in the biosynthesis of the components of the gentamicin complex].
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