Possible Interaction: Cobalt and Hydrogen Peroxide

“ Cobalt was less effective in inhibiting peroxidation stimulated by organic hydroperoxides.”

“In this study, chemiluminescence of creatinine with hydrogen peroxide has been reported for the first time, and its chemiluminescence is remarkably enhanced in the presence of cobalt ions.”

“Since then, we have reported that various metal compounds, such as cobalt , nickel, and ferric nitrilotriacetate, directly cause site-specific DNA damage in the presence of H2O2.”

“Incubation with cobalt or with desferrioxamine, however, leads to a decrease of the intracellular H2O2 level as revealed by the dihydrorhodamine 123 technique, perhaps causing the well-known enhanced erythropoietin production.”

“Exposure to Co also increased the levels of MDA, PCO, H2O2 , and AOPP, while Na+K+-ATPase and Mg2+-ATPase, AChE, and BuChE activities decreased in the cerebrum and cerebellum of suckling pups.”

“Computational modeling demonstrates these electronically modified cobalt atoms will enhance the hydrogen peroxide productivity during oxygen reduction reaction in acid, providing insights into the design of electroactive materials for effective peroxide production.”

“ Cobalt corroles promote O2 reduction to H2O2.”

“It is concluded that cobalt stimulates a signal cascade with cytochrome b as receptor and H2O2 as second messenger for regulating erythropoietin production.”