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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Cobalt
drug:
Gentamicin
Research Papers that Mention the Interaction
“In a parental strain, KY11510, cobalt ion stimulated gentamicin C1 production and suppressed sagamicin production.”
Sagamicin and the related aminoglycosides: fermentation and biosynthesis. III. Isolation and characterization of Micromonospora sagamiensis mutants blocked in gentamicin C1 pathway.“It was … addition of cobalt ions or vitamin B12 to the fermentation medium … an increase in the level of gentamicin accumulation, the relative content of the most methylated components C1 and C2 in the gentamicin … being increased, while the content of the least methylated components CIa and "minors" decreased.”
“Stimulation of gentamicin biosynthesis by cobalt was inversely proportional to the time of the trace element addition.”
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