Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Cobalt and Alpha-Ketoglutaric Acid

supplement:

Cobalt

Research Papers that Mention the Interaction

Cobalt treatment for 8 days significantly depressed respiration of isolated rat heart mitochondria when citrate or α-ketoglutarate but not succinate was utilized as added substrate.
Canadian journal of biochemistry  •  1968  |  View Paper
This hypothesis was supported by the finding that cobalt (II) inhibited oxidation of α-ketoglutarate and pyruvate by rat liver mitochondria during a prolonged incubation without the addition of phosphate acceptor1.
Nature  •  1963  |  View Paper