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“ Cobalt treatment for 8 days significantly depressed respiration of isolated rat heart mitochondria when citrate or α-ketoglutarate but not succinate was utilized as added substrate.”
Canadian journal of biochemistry • 1968 | View Paper
“This hypothesis was supported by the finding that cobalt (II) inhibited oxidation of α-ketoglutarate and pyruvate by rat liver mitochondria during a prolonged incubation without the addition of phosphate acceptor1.”