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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Coal Tar and Tretinoin

supplement:

Tretinoin

Research Papers that Mention the Interaction

Downregulation of basal P4501A1 expression and antagonism of coal tar mediated P4501A1 induction by RA may be a mechanism involved in chemo-prevention of skin and other epithelial cancer by RA.
Interestingly, P4501A1 mRNA expression induced by coal tar or glucocorticoid (clobetasol) was reduced 46 (n = 10, P = 0.003) and 69% (n = 5, P < 0.05) respectively by RA co-application.
Carcinogenesis  •  1995  |  View Paper