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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Clozapine and Tyrosine

supplement:

Tyrosine

Research Papers that Mention the Interaction

Consistently, clozapine reduced insulin effect on insulin receptor (IR) by 40% and on IR substrate‐1 (IRS1) tyrosine phosphorylation by 60%.
Journal of cellular physiology  •  2012  |  View Paper
Tyrosine (25 or 50 mg/kg IP) administered 30 min after clozapine (10 mg/kg IP) augmented clozapine-induced MPFC but not striatal DA release.
Neuroscience Letters  •  2004  |  View Paper
Given 30 minutes after clozapine (10 mg/kg), tyrosine (50 mg/kg) significantly prolonged the clozapine-induced increase in MPFC extracellular DA concentrations but had no effect in the striatum.
Neuropsychopharmacology  •  2001  |  View Paper