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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Clozapine and Melatonin

supplement:

Melatonin

Research Papers that Mention the Interaction

Both clozapine and spiperone per se significantly increased melatonin levels, whereas SCH 23390 was ineffective.
The Journal of pharmacology and experimental therapeutics  •  2000  |  View Paper
Clozapine , a D2C/D4 antagonist, also enhanced the nocturnal level of melatonin , whereas raclopride, a D2A antagonist, did not.
Journal of neurochemistry  •  1996  |  View Paper
Spiroperidol, clozapine , haloperidol and sulpiride significantly increased melatonin content in the light-exposed retina, but had no effect on the activity of hydroxyindole-O-methyltransferase.
Neuroscience Letters  •  1994  |  View Paper