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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Clotrimazole
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ CLT inhibits Ca2+ -ATPase and Ca2+ transport with a KI of 35 μm.”
Clotrimazole Inhibits the Ca2+-ATPase (SERCA) by Interfering with Ca2+ Binding and Favoring the E2 Conformation*“IK Ca was suppressed by charybdotoxin (50 nM), iberiotoxin (10 nM) or clotrimazol (1 μM), but not by apamine (100 nM).”
“External Ca2+ removal partly inhibited the Ca2+ signals by reducing both the initial rise and the decay phase, indicating that clotrimazole triggered both Ca2+ influx and Ca2+ release.”
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