supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Clopidogrel
supplement:
Ginkgo Biloba Whole
Research Papers that Mention the Interaction
“As expected, pretreatment of high dose GBE significantly increased the Cmax and AUC0–∞ of the clopidogrel active metabolite.”
“Compared to rats without GBE pretreatment, administration of 4 mg/kg, 20 mg/kg, and 100 mg/kg of GBE significantly decreased the Cmax and the AUC0–∞ of clopidogrel in a dose‐dependent manner.”
“Our study suggested that the awareness of the potential herb–drug interactions between GBE and clopidogrel should be increased in clinical practice.”
“The in vitro study using rat liver microsomes revealed that GBE significantly induced the conversion of clopidogrel into its active metabolite.”
Effect of Ginkgo Biloba Extract on the Pharmacokinetics and Metabolism of Clopidogrel in Rats
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback