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Discover Supplement-Drug Interactions

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Last Updated: a month ago

Possible Interaction: Clopidogrel and Ginkgo Biloba Whole

Research Papers that Mention the Interaction

As expected, pretreatment of high dose GBE significantly increased the Cmax and AUC0–∞ of the clopidogrel active metabolite.
Compared to rats without GBE pretreatment, administration of 4 mg/kg, 20 mg/kg, and 100 mg/kg of GBE significantly decreased the Cmax and the AUC0–∞ of clopidogrel in a dose‐dependent manner.
Our study suggested that the awareness of the potential herb–drug interactions between GBE and clopidogrel should be increased in clinical practice.
The in vitro study using rat liver microsomes revealed that GBE significantly induced the conversion of clopidogrel into its active metabolite.
Phytotherapy research : PTR  •  2016  |  View Paper