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The American journal of physiology • 1997 | View Paper
“The combined treatment with clonidine + yohimbine reduced REM sleep, but not as extensively as clonidine alone; the Hjorth parameters were without significant alterations compared to placebo.”
“The physiological hypotonia was enhanced by clonidine and the combined treatment with clonidine + yohimbine.”
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi • 2006 | View Paper
“The effects of clonidine were blocked by yohimbine , a specific alpha2-adrenergic antagonist, but not by phentolamine, an alpha1-adrenergic antagonist.”
“In addition, clonidine (pD2 = 10.28) inhibited electrical field stimulation-evoked contractile responses in human saphenous vein which were blocked by yohimbine (30 nM, pA2 = 9.92) but did not alter the (R)-alpha-methylhistamine dose response curve.”
European journal of pharmacology • 1999 | View Paper
“ Clonidine (3 × 10−9 to 3 × 10−7 M) blocked concentration‐dependently the contractile response to electrical field stimulation of human prostate and this inhibitory effect was reversed by yohimbine (10−7 M).”
British journal of pharmacology • 1995 | View Paper
“Cirazoline was the most potent to inhibit [3H]clonidine binding although yohimbine was also able to displace binding in the human NRL but with lower apparent affinity.”
European journal of pharmacology • 1989 | View Paper
“Functional studies on the conscious guinea-pig have shown that clonidine can potentiate the bronchoconstrictor effects of acetylcholine, histamine and serotonin (fig. 3) and that this potentiating effect is specifically inhibited by yohimbine and piperoxan (fig. 4).”