supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Quinine reduced specific binding incompletely (73%) with Ki values of 75 nM and 133 mM. Clonidine , N‐allyl‐clonidine (alinidine), and quinine inhibited native KATP channels as well as Kir6.2DC26 channels.”
Specificity of Nonadrenergic Imidazoline Binding Sites in Insulin‐Secreting Cells and Relation to the Block of ATP‐Sensitive K1 Channels“Many drugs such as clonidine, guanabenz, methamphetamine, imipramine, clomipramine, nortriptyline, quinine , xylazine, ephedrine, and diphenhydramine strongly inhibited the [3H]clonidine uptake with Ki values between 0.15 and 1 mM.ConclusionsClonidine is transported by a carrier-mediated process.”
“Diphenhydramine, guanabenz, procainamide, tryptamine, quinine , and quinidine, but not choline markedly inhibited clonidine uptake.”
“Several cationic drugs such as clonidine, quinine , quinidine, and diphenhydramine strongly inhibited the [3H]clonidine uptake with Ki values around 1 mM. Conclusions.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback