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“When the …-adrenoreceptor agonist clonidine (2.5 µg/kg intracerebroventricularly) was administered 3 days after the 5-day treatment period with oxytocin or saline, plasma levels of insulin and CCK increased significantly (p < 0.05) in the oxytocin-treated rats, when compared to saline-treated controls receiving clonidine only.”
“The present study shows that subchronic oxytocin treatment increases the effects of clonidine on blood pressure and spontaneous motor activity in rats.”
Journal of the autonomic nervous system • 1999 | View Paper
“ Clonidine , an alpha-2 agonist, inhibited basal Posm and oxytocin , isoproterenol and theophylline stimulated Posm, but did not alter the hydrosmotic effect of exogenous cAMP.”