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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Analysis of the time course for platelet magnesium showed that the intracellular magnesium loss induced by clonidine (10 pg/mL) was time-dependent.”
Effects of alpha- and beta-adrenergic stimulation on free magnesium concentrations in platelets from healthy and obese individuals.“IN drug competition studies using 1.0 nM 3H-clonidine, 100 microM GTP reduced the affinity of clonidine and increased the affinity of yohimbine, whereas 10 mM magnesium increased the affinity of clonidine and reduced the affinity of yohimbine.”
Magnesium reduces affinities of antagonists at rat cortex alpha 2-adrenergic receptors labeled with 3H-clonidine: evidence for heterogeneity of alpha 2-receptor conformations with respect to antagonists.“5 At low concentrations the divalent cations, magnesium (1 mm) and manganese (0.1 mm), produced enhancement of [3H]‐clonidine binding.”
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