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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Clonazepam
supplement:
Tryptophan
Research Papers that Mention the Interaction
“ Abstract Clonazepam induced a dose-dependent increase in cerebral 5-hydroxytryptamine (5HT), 5-hydroxyindoleacetic acid (5HIAA) and tryptophan levels in mice.”
Clonazepam induces decreased serotoninergic activity in the mouse brain“2 Acute administration of clonazepam and diazepam but not diphenylhydantoin raised cerebral tryptophan levels; chronic administration of clonazepam caused a smaller elevation of cerebral tryptophan but chronic administration of diazepam still caused a large rise in cerebral tryptophan.”
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