“Simultaneous treatment with melatonin and clomiphene produced an inhibitory effect similar to that obtained with melatonin alone.”
“The … melatonin was able to … effect of clomiphene , which is probably exerted at the hypothalamic level, but not the action of LH-RH on the pituitary, appears to indicate … the hypothala-mus may be the site involved in the inhibitory effect of the pineal principle on the reproductive function.”