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Discover Supplement-Drug Interactions

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Possible Interaction: Clofibrate and Vitamin C

supplement:

Vitamin C

Research Papers that Mention the Interaction

In older people, no consistent pattern of serum-cholesterol change was seen, but in patients with a history of atherosclerosis, most of whom were on clofibrate and/or anticoagulants, the serum-cholesterol increased in the weeks when vitamin-C supplements were given.
Lancet  •  1972  |  View Paper
It is concluded that vitamin C plays an important role in the control of cholesterol metabolism in hypercholesterolemic guinea-pigs receiving clofibrate or diosgenin.
The cholesterol lowering actions of clofibrate and diosgenin were enhanced by daily supplementary vitamin C in hypercholesterolemic guinea-pigs.
International journal for vitamin and nutrition research. Supplement = Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Supplement  •  1982  |  View Paper