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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Clofibrate and Tryptophan

supplement:

Tryptophan

Research Papers that Mention the Interaction

Clofibrate was inhibitory to tryptophan metabolism as a whole, affecting the glutarate pathway more (decreased to 37% of control) than the kynureninase flux (decreased to 64% of control).
Biochemical pharmacology  •  1996  |  View Paper
When clofibrate was injected in vivo so that plasma total tryptophan concentration was decreased by 45% but neither free tryptophan nor competing amino acid concentrations were altered, then uptake from a bolus of the rat's own plasma was unchanged.
Journal of neurochemistry  •  1980  |  View Paper