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Discover Supplement-Drug Interactions

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Possible Interaction: Clofibrate and Polyunsaturated Fatty Acids

Research Papers that Mention the Interaction

It is concluded that addition of clofibrate treatment to patients who are on a diet enriched with polyunsaturated fats is associated with a change from polyunsaturated to monounsaturated fatty acids in the plasma lipid esters but does not significantly effect the ratio between polyunsaturated and saturated fatty acids.
The fatty acid changes caused by clofibrate treatment and counteracted by an increased amount of polyunsaturated fat in the diet.
Atherosclerosis  •  1980  |  View Paper
Induction of this enzyme by clofibrate or by certain high-fat diets increases mitochondrial capacity for the degradation of polyunsaturated fatty acids.
Biochimica et biophysica acta  •  1983  |  View Paper