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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
drug:
Clofibrate
supplement:
Polyunsaturated Fatty Acids
Research Papers that Mention the Interaction
“It is concluded that addition of clofibrate treatment to patients who are on a diet enriched with polyunsaturated fats is associated with a change from polyunsaturated to monounsaturated fatty acids in the plasma lipid esters but does not significantly effect the ratio between polyunsaturated and saturated fatty acids.”
“The fatty acid changes caused by clofibrate treatment and counteracted by an increased amount of polyunsaturated fat in the diet.”
Changes in the fatty acid composition of the plasma lipid esters during lipid-lowering treatment with diet, clofibrate and niceritrol. Reduction of the proportion of linoleate by clofibrate but not by niceritrol.“Induction of this enzyme by clofibrate or by certain high-fat diets increases mitochondrial capacity for the degradation of polyunsaturated fatty acids.”
Beta-oxidation of polyunsaturated fatty acids having double bonds at even-numbered positions in isolated rat liver mitochondria.
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