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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Clofibrate
supplement:
Niacin
Research Papers that Mention the Interaction
“The combination of Clofibrate with nicotinic acid is not of greater value than the monotherapy with Clofibrate (Atromid S).”
[Combination or monotherapy of hyperlipoproteinemia typus IIb, IV, V with clofibrate and m-inositolnicotinate or clofibrinic acid (author's transl)].“Combined treatment with clofibrate and niacin resulted in a sustained decrease in plasma triglyceride levels for 4 months.”
“Two type III patients treated with nicotinic acid and clofibrate showed a sharp decrease in their VLDL apoB synthesis rates.”
“The content of liver total nicotinamide was higher in the clofibrate group than in the control group.”
Increased conversion ratio of tryptophan to niacin by the administration of clofibrate, a hypolipidemic drug, to rats.“The results show that the combined hypolipidemic effect of clofibrate and nicotinic acid in rats is accompanied by changes in the pharmacokinetics of the drugs, the most pronounced being a decrease in the rate of elimination of nicotinic acid.”
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