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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Clofibrate and Lauric Acid

supplement:

Lauric Acid

Research Papers that Mention the Interaction

Both clofibrate and DEHP specifically induced (approximately 10-fold) the 12-hydroxylation of lauric acid in a dose-dependent manner and only marginally increased the associated 11-hydroxylase activity.
Biochemical pharmacology  •  1988  |  View Paper
In the rat, clofibrate administration specifically increased the hepatic microsomal omega-hydroxylation of lauric acid approximately 28-fold, which contrasted with the specific increase in (omega - 1)-hydroxylation caused by phenobarbital administration.
Drug metabolism and disposition: the biological fate of chemicals  •  1982  |  View Paper