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Last Updated: 2 years ago

Possible Interaction: Clofibrate and Glutathione

supplement:

Glutathione

Research Papers that Mention the Interaction

CFB pretreatment significantly enhanced the levels of superoxide dismutase (SOD) and glutathione (GSH), and markedly decreased the malonaldehyde (MDA) content.
Life sciences  •  2018  |  View Paper
Repeated treatment with clofibrate (CFB) significantly increased hepatic glutathione (GSH) content and also diminished acetaminophen's (APAP) selective protein arylation, GSH depletion, and severity of hepatocellular necrosis.
Toxicology and applied pharmacology  •  1996  |  View Paper
At 4 hr after APAP treatment, hepatic glutathione (GSH) depletion and selective arylation of the major APAP target proteins were both greatly diminished by CFB pretreatment.
Pretreatment with CFB also produced a significant elevation in hepatic GSH.
Toxicology and applied pharmacology  •  1994  |  View Paper
Clofibrate administration produced decrease in gamma-glutamyltranspeptidase (GGT) activity with concomitant increase in glutathione concentration.
Biochemistry international  •  1988  |  View Paper
CLOF induced a low incidence of GSH positive foci; nodules showed universally lower levels of catalase and GSH.
Toxicology  •  1987  |  View Paper