Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 months ago

Possible Interaction: Clofibrate and Glutathione

supplement:

Glutathione

Research Papers that Mention the Interaction

CFB pretreatment significantly enhanced the levels of superoxide dismutase (SOD) and glutathione (GSH), and markedly decreased the malonaldehyde (MDA) content.
Life sciences  •  2018  |  View Paper
At 4 hr after APAP treatment, hepatic glutathione (GSH) depletion and selective arylation of the major APAP target proteins were both greatly diminished by CFB pretreatment.
Pretreatment with CFB also produced a significant elevation in hepatic GSH.
Toxicology and applied pharmacology  •  1994  |  View Paper
Inhibitory effects on development of glutathione S-transferase placental form-positive liver cell foci were observed with clofibrate.
Japanese journal of cancer research : Gann  •  1992  |  View Paper
CLOF induced a low incidence of GSH positive foci; nodules showed universally lower levels of catalase and GSH.
Toxicology  •  1987  |  View Paper
A slight decrease in glutathione S-transferase activity was found in the group treated with clofibrate.
Toxicology  •  1985  |  View Paper