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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Clofibrate
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“The response to stimulation by adrenocorticotrophic hormone of plasma cortisol and urinary 17-hydroxy levels was significantly reduced by treatment with clofibrate , but unchanged by lovastatin.”
Plasma Cortisol and Testosterone in Hypercholesterolaemia Treated with Clofibrate and Lovastatin“ Clofibrate also inhibited the stimulation by ACTH of the formation of corticosterone by rat adrenal quarters; the extent of the inhibition by clofibrate was concentration-dependent.”
Clofibrate inhibits lipid synthesis and ACTH-stimulated steroidogenesis by rat adrenal tissue.
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