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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Clofazimine
supplement:
Serum Albumin, Human
Research Papers that Mention the Interaction
“ Clofazimine impelled rise in α-helical structure in HSA as observed from far-UV CD spectra while there are minor alterations in tertiary structure of the protein.”
“ Clofazimine interacts strongly with HSA inducing secondary structure in the protein and slight alterations in protein topology as suggested by dynamic light scattering results.”
“Moreover, docking results indicate that clofazimine binds to hydrophobic pocket near to the drug site II in HSA.”
“The UV–visible spectra showed increase in absorbance upon interaction of HSA with clofazimine which further reveals formation of the drug–albumin complex.”
Insight into the interaction of antitubercular and anticancer compound clofazimine with human serum albumin: spectroscopy and molecular modelling
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