Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 months ago

Possible Interaction: Clofarabine and Serum Albumin, Human

Research Papers that Mention the Interaction

Binding of clofarabine with HSA and AAG induced ordered structures in both proteins and lead to molecular compaction.
Clofarabine binds to HSA near to drug site II.
The Gibbs free energy change was found to be negative for the interaction of clofarabine with AAG and HSA indicating that the binding process is spontaneous.
The results obtained from fluorescence quenching experiments demonstrated that the fluorescence intensity of HSA and AAG is quenched by clofarabine and the static mode of fluorescence quenching is operative.
Journal of pharmaceutical and biomedical analysis  •  2017  |  View Paper