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Discover Supplement-Drug Interactions

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Possible Interaction: Clofarabine and Serum Albumin, Human

Research Papers that Mention the Interaction

Binding of clofarabine with HSA and AAG induced ordered structures in both proteins and lead to molecular compaction.
Clofarabine binds to HSA near to drug site II.
The Gibbs free energy change was found to be negative for the interaction of clofarabine with AAG and HSA indicating that the binding process is spontaneous.
The results obtained from fluorescence quenching experiments demonstrated that the fluorescence intensity of HSA and AAG is quenched by clofarabine and the static mode of fluorescence quenching is operative.
Journal of pharmaceutical and biomedical analysis  •  2017  |  View Paper