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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Clobetasol
supplement:
Tretinoin
Research Papers that Mention the Interaction
“Interestingly, P4501A1 mRNA expression induced by coal tar or glucocorticoid clobetasol ) was reduced 46 (n = 10, P = 0.003) and 69% (n = 5, P < 0.05) respectively by RA co-application.”
Retinoic acid antagonizes basal as well as coal tar and glucocorticoid-induced cytochrome P4501A1 expression in human skin.“The PA‐FABP mRNA response to RA was reduced by approximately 50% when patients concurrently were treated with RA and 0.025% clobelasol propionate (CLO) for 48 and 96 h, whereas treatment with CLO alone resulted in PA‐FABP transcript levels not significantly different from vehicle‐treated skin.”
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