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Last Updated: 23 days ago

Possible Interaction: Clioquinol and Iron, Dietary

supplement:

Iron, Dietary

Research Papers that Mention the Interaction

Here we show that clioquinol inhibits the activity of mammalian CLK-1 in cultured cells, an inhibition that can be blocked by iron or cobalt cations, suggesting that chelation is involved in the mechanism of action of clioquinol on CLK-1.
Journal of Biological Chemistry  •  2009  |  View Paper
We found that CQ could remarkably improve the motor and non-motor deficits, which were based on the reduction of iron content and ROS level in the SN and further improvement in pathology.
Aging  •  2020  |  View Paper
Clioquinol increased the intracellular contents of iron and zinc as well as calcium as measured by ICP-AES.
Metallomics : integrated biometal science  •  2019  |  View Paper
Metallomic analysis revealed, however, that CQ reduced potassium and magnesium levels in the brain MEF and also lowered brain iron levels.
Journal of pharmaceutical sciences  •  2019  |  View Paper