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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Clindamycin
supplement:
Tretinoin
Research Papers that Mention the Interaction
“For example, the combination of clindamycin and tretinoin in a unique vehicle formulation allows for progressive follicle penetration and decreased irritation, resulting in increased efficacy.”
Newer approaches in topical combination therapy for acne.“The addition of clindamycin to tretinoin enhances the comedolytic efficacy of tretinoin in moderate-to-severe acne of the face.”
“The comedolytic activity of tretinoin and the anti-inflammatory efficacy of clindamycin accelerate resolution of all types of acne lesions without affecting the safety of both compounds.”
“Based on our previous research in acute myeloid leukemia (AML), we reasoned verlindamycin may also unblock neuroblastoma differentiation when combined with all-trans-retinoic acid (ATRA).”
“Indeed, co-treatment with verlindamycin and ATRA strongly induced differentiation regardless of MYCN status, but in MYCN-expressing cells, protein levels were strongly diminished.”
The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme.
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