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“Results of this study indicate that the effectiveness of epinephrine to inhibit insulin-stimulated glucose uptake is severely diminished in muscle from rats pretreated with clenbuterol.”
“Feeding CB (20 mg/kg diet) to mice for 1, 3 or 6 wk decreased adipocyte sensitivity to EPI or CB by 35-45%, with no differences in magnitude of this desensitization across time.”
“ Clenbuterol treatment produced desensitization of the beta 2-adrenoceptor-mediated effect and thus reduced the vasodilator response induced by isoproterenol and increased the vasoconstriction produced by epinephrine but not that caused by NE.”