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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Citrulline
drug:
Teduglutide
Research Papers that Mention the Interaction
“ Citrulline levels may correlate with PS changes in response to teduglutide and more research may reveal a relationship between citrulline levels within the heterogeneous population of patients with SBS-IF.”
“In all subgroups, patients treated with teduglutide showed numerically greater increases in plasma citrulline at Week 24 compared with placebo.”
Citrulline correlations in short bowel syndrome-intestinal failure by patient stratification: Analysis of 24 weeks of teduglutide treatment from a randomized controlled study.“ Teduglutide increased plasma concentrations of citrulline , a biomarker of mucosal mass.”
“Villus height, plasma citrulline concentration and lean body mass were significantly increased with teduglutide compared with placebo.”
“Conclusions:In 2 phase III studies, patients receiving teduglutide had significant increases in plasma citrulline at Week 24 compared with patients receiving placebo.”
Effect of Teduglutide, a Glucagon-like Peptide 2 Analog, on Citrulline Levels in Patients With Short Bowel Syndrome in Two Phase III Randomized Trials
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