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Last Updated: 2 years ago

Possible Interaction: Citrulline and Nitroarginine

supplement:

Citrulline

Research Papers that Mention the Interaction

The addition of L-citrulline (1 mM) added before L-NNA was without effect on the relaxant responses to field stimulation but was able to prevent the inhibition produced by L-NNA.
The inhibition produced by L-NNA was reversed by either L-arginine or L-citrulline.
The Journal of pharmacology and experimental therapeutics  •  1994  |  View Paper
After 6 days of culture with IL-4, human monocytes released detectable amounts of nitrite and L-citrulline that were inhibited in the presence of nitro-L-arginine (1 mM).
Cellular immunology  •  1995  |  View Paper
Local infusion of N-nitro-L-arginine (0.5 mM) slightly decreased basal citrulline levels in the nucleus accumbens throughout the entire period of the infusion, whereas dizocilpine maleate (50 microM) had no long-lasting effect.
Neuroscience Letters  •  2006  |  View Paper
3 An inhibitor of constitutive nitric oxide synthase (NOS), Nω‐nitro‐L‐arginine (NNA) prevented the ATP‐induced increased accumulation of L‐citrulline and the relaxation effect of ATP.
The Journal of physiology  •  2001  |  View Paper
Removal of calcium from the medium or addition of NG-nitro-L-arginine strongly inhibited both spontaneous and electrically induced production of [3H]citrulline.
The American journal of physiology  •  1999  |  View Paper
L-Citrulline , like L-arginine, reversed L-NNA inhibition of outward currents; only L-arginine reversed inhibition of outward currents by an antibody to argininosuccinate synthetase.
The American journal of physiology  •  1998  |  View Paper
The synthesis of citrulline from arginine decreased by >88% in the presence of L-NNA.
The American journal of physiology  •  1996  |  View Paper
In vivo administration of the NO synthase inhibitor L‐nitroarginine (L‐NARG; 100 μM) significantly reduced NO2‐, NO3‐ and CIT levels and prevented NMDA, kainate or KCI‐evoked increases.
The European journal of neuroscience  •  1996  |  View Paper
L-NNA (1 mM) inhibited NOS catalytic activity, assessed ex vivo using the citrulline assay , by 95 +/- 9% (P < 0.001).
The American journal of physiology  •  1995  |  View Paper
It was also possible to show that the selective NO synthase inhibitor L-NOARG decreased the formation of citrulline.
Brain Research  •  1994  |  View Paper
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