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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Citrulline
drug:
Indomethacin
Research Papers that Mention the Interaction
“ IDMT increases blood DAO activity, I-FABP concentration, neutrophil and eosinophil numbers; intestinal MMP3 … levels, MPO activity, and MDA concentration; but reduces the plasma concentration of citrulline (synthesized exclusively by enterocytes of the small intestine), intestinal GSH-Px …, and mRNA levels for villin, I-FABP, TRPV6, AQP10, and KCNJ13.”
Establishment of a porcine model of indomethacin-induced intestinal injury.“ Indomethacin increased both NO<sub>x</sub>, eNOS and L-citrulline levels.”
“On the other hand, attenuation effect of l-citrulline on CSD propagation velocity was prevented not only by l-NAME but also by indomethacin.”
l-Citrulline ameliorates cerebral blood flow during cortical spreading depression in rats: Involvement of nitric oxide- and prostanoids-mediated pathway.“Indeed, indomethacin (10 microM) completely suppressed the increment in citrulline levels induced by the hormone.”
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