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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Citric Acid
supplement:
Vitamin C
Research Papers that Mention the Interaction
“Evaluation of (1) age-related dietary trends over time and (2) factors involved in iron absorption leads to the hypothesis that the combination of citric acid and ascorbic acid (a synergistic pair of strong enhancers) is instrumental in causing a deleterious increase in iron load in aging populations.”
“Iron overload may be the most important common etiologic factor in the development of the diseases mentioned; therefore, the synergistic combination of citric and ascorbic acids may play a major role in our worsening disease statistics.”
Proposed role for a combination of citric acid and ascorbic acid in the production of dietary iron overload: a fundamental cause of disease.“In preliminary experiments, pre-impregnation of the strips with citric acid increased the recovery of standard ascorbic acid from 37 to 89% and significantly reduced loss of water from the strips over a 3 min period.”
“The benefit of citric acid on iron-calcium interaction is enhanced by ascorbic acid.”
Calcium bioavailability and iron-calcium interaction in orange juice.“A significant decrease in PPO activity was detected in fruits when treated with both AA and CA.”
“Considering the results, foliar application of AA and CA , either alone or in combination improved the quality and nutraceutical properties of ‘Red Spur’ apple.”
Foliar application of ascorbic and citric acids enhanced ‘Red Spur’ apple fruit quality, bioactive compounds and antioxidant activity“Higher CA level and lower EDTA level could trigger the synthesis of ascorbic acid and higher level of EDTA could trigger the synthesis of glutathione.”
“The addition of citric and ascorbic acids improved the stability of the flavonoids, but encapsulation of green rooibos extract with ascorbic acid in nanomicelles did not offer additional stability.”
“The significant oxidizing effects of citric acid at 10% were reversed (P<0.05) by ascorbic acid.”
“ Ascorbic acid acted as a potent inhibitor of the reaction, while other organic acids ( citric and benzoic) had little to no inhibitory effect.”
“In the case of citric and malic acids, the addition of ascorbic acid reduced the soluble iron.”
“The decomposition of ascorbic acid in real samples should be carried out at 50 °C because citric acid , which is usually present in the samples under study, retards the copper(II)-catalysed oxidation of ascorbic acid.”
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