Possible Interaction: Citicholine and Phospholipids

“ Citicoline activates biosynthesis of phospholipids in neuronal membranes, increases brain metabolism as well as norepinephrine and dopamine levels in the central nervous system, and has neuroprotective effects during hypoxia and ischemia.”

“Experimental studies have shown that the administration of CDP-choline increases the total amount of phosphatidylcholine and other related phospholipids in the brain and in some cases may enhance neurotransmission.”

“ Citicoline activates biosynthesis of structural phospholipids of neuronal membranes, increases brain metabolism, and acts upon the levels of different neurotransmitters.”

“ CDP-choline activates the biosynthesis of structural phospholipids in the neuronal membranes, increases cerebral metabolism and acts on the levels of various neurotransmitters.”

“ Citicoline accelerates resynthesis of phospholipids and enhances neuroregenerative processes after experimental stroke in rats.”

“These data show that citicoline improves frontal lobe bioenergetics and alters phospholipid membrane turnover.”

“ Citicoline modulates phospholipids metabolism and neurotransmitter levels and appears to improve cognition in some central nervous system disorders.”

“In addition, NEC damage reduced intestinal tissue membrane phospholipids, whereas CDP-choline significantly enhanced total phospholipid and phosphatidylcholine levels.”

“Lung tissue and BAL phospholipid contents showed significant increases after CDP-choline administration.”

“ CDP‐choline in the medium produced a concentration dependent reduction in the amount of radio‐label in phosphocholine and phospholipid but it did not alter choline uptake into the myocytes.”